Discovery & Pre-Clinical
Accelerating Biologics Development
from Concept to Clinic
The discovery and preclinical phase is critical in the lifecycle of large molecule therapeutics, laying the foundation for successful clinical development and commercialization.
Protein Sciences & Molecular Biology
Mammalian cell culture remains the gold standard for producing complex, glycosylated proteins such as monoclonal antibodies (mAbs), fusion proteins and therapeutic enzymes.
1
Strain Enhancement
Gene optimization, codon usage adjustment and vector design to maximize yield and stability.
2
Transient Expression
Rapid protein production using mammalian or microbial systems, coupled with advanced chromatography for high purity.
3
Molecular Biology Services
Gene synthesis, cloning, site-directed mutagenesis and vector construction tailored to therapeutic targets.
4
Host Selection
Expression systems E. coli, Bacillus subtilis, Pichia pastoris, Saccharomyces cerevisiae, CHO, HEK293 based on protein needs.
Antibody Generation
We provide end-to-end antibody development services to generate high-affinity, target-specific antibodies for research and therapeutic use.
1
Immunogen/Antigen Design
Recombinant proteins, peptides or conjugates designed to elicit robust immune responses.
2
Hybridoma & Polyclonal Antibody Production
Custom generation, screening and cloning of monoclonal antibodies; broad immune response via polyclonal antibodies.
3
Scale-Up & GMP Production
Large-scale antibody manufacturing under GMP conditions, including purification and quality control.
Cell Line Development
Robust cell line development is essential for consistent biologics production.
1
Microbial & Mammalian Cell Lines
Development and optimization of E. coli, Bacillus subtilis, yeast, CHO, HEK293 and Sp2/0 cell lines.
2
Chromatography Purification
Low to high-pressure chromatography tailored to protein characteristics.
3
High-Density Cultivation
Advanced bioreactor systems for maximizing protein yield.
4
Clone Stability & Screening
Ensuring long-term expression stability and product consistency.
Preclinical Evaluation & Non-GMP Manufacturing
Our preclinical services provide critical data on safety, efficacy and pharmacokinetics to support IND filings and clinical trial readiness.
1
Efficacy & Mechanism Studies
In vitro and in vivo models to assess therapeutic potential and mode of action.
2
Non-GMP Manufacturing
Research-grade protein production at scales from 2L to 500L to support early-stage studies and formulation development.
3
ADME & Toxicology
Absorption, distribution, metabolism, excretion and toxicity profiling in compliance with regulatory guidelines.