Peptides
Peptide Synthesis:
Precision, Purity and Scalability
At Anthem, we specialize in the synthesis of high-quality peptides of up to 40 amino acids, catering to therapeutic and research applications.
Comprehensive Peptide Synthesis Solutions
We utilize advanced techniques across Solid Phase Peptide Synthesis (SPPS), Solution Phase Synthesis (SPS), and hybrid approaches to ensure flexibility and efficiency in production.
Expertise in Peptide Chemistry
Protection/Deprotection Strategies
Mastery in N-terminal and C-terminal techniques for precise peptide bond formation.
Unnatural Amino Acids
Capabilities to synthesize peptides with custom amino acid modifications.
Coupling Reagents
Skilled in using HATU, TBTU, PyBrop, and more for efficient amino acid coupling.
Route Design
Tailored synthetic routes to optimize yield, purity, and scalability.
Analytical Development
Advanced techniques for characterization, including Amino Acid Sequencing and TFA Acetate Salt Analysis.
Peptide Purification Excellence
Our purification systems ensure high-purity peptide products:
Preparative HPLC | Biotage and DAC Systems | Ion Exchange Chromatography
Comprehensive Peptide Services
Route Scouting/Design | Process Optimization | Technology Transfer | Process Validation | Commercial Supply
Specialization in Solid Phase Peptide Synthesis
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Linear Peptides: Up to 50 amino acids, natural or modified.
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Branched and Cyclic Peptides for complex applications.
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Multi-Disulfide Bridging Peptides with intricate structural requirements.
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Convergent Synthesis for enhanced efficiency in peptide production.
Lyophilization
Freeze-drying for stabilization at both lab and commercial scales.
RP-HPLC & Biotage Purification
Ensuring consistent high-purity products.
Ion Exchange Chromatography
Advanced purification for large-scale applications.
Isolation and Filtration Expertise
State-of-the-Art Infrastructure
Our advanced facilities provide unmatched capabilities for peptide synthesis:
Unit II: Liquid Phase Synthesis
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Scalable systems ranging from 300L to 10KL for solution phase synthesis.
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Equipped with 200 mm and 300 mm DAC columns for high-efficiency purification.
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Large-scale lyophilization capabilities with dual 100L lyophilizers.
Unit I (GMP Facility): Solid Phase Peptide Synthesis
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Capacity for 0.5–50 grams of resin with reactors up to 3000L.
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Advanced agitation techniques for optimal mixing.
Why Choose Anthem for Peptides?
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Advanced Infrastructure
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Expert Team
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Global Standards
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End-to-End Solutions